ECTS Abstracts (2015) 1 P56

Routine blood-samples as predictors of re-operation due to post-operative infection in hip fracture patients

Debbie Norring-Agerskov2, Adbu Mohamed2, Henrik Løvendahl Jørgensen2, Troels Riis3, Benn Rønnow Duus1, Jes Bruun Lauritzen1 & Jesper Jørgen Hvolris1


1Department of Orthopaedic Surgery, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark; 2Department of Clinical Biochemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark; 3Department of Clinical Pharmacology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.


Background: Several studies have shown an increased risk of both morbidity and mortality in hip fracture patients. There have been numerous studies focusing on different predictors of mortality. However, there is not much literature investigating postoperative complications and morbidity. The purpose of this study was to examine the relationship between in-hospital routine biochemical markers taken at admission and the risk of reoperation due to postoperative infection following a hip fracture.

Methods: A search on all hip fracture patients from Bispebjerg Hospital was conducted from the period October 2008 – June 2013, N=2,200. On this group of patients, a search for every reoperation caused by deep infection was conducted. Patients were included in the study if reoperation was within 3 months, resulting in 25 cases. For every case, two randomly chosen hip fracture patients from the hip fracture database from Bispebjerg Hospital matching in sex and age and without postoperative infection were found, resulting in 50 control patients. From the laboratory database blood-samples taken at admission were extracted.

Results: Two markers were found to have a statistically significant association with the risk of reoperation due to postoperative infection: CRP above 26 mg/l (OR 4.84 [1.69;13.87], p=0.002) and albumin lower than 35 g/l (OR 4.57 [1.64;12.73], p=0.003).

Conclusion: This study shows that CRP and albumin can be used for predicting the risk of reoperation due to postoperative infection in hip fracture patients.

Disclosure: The authors declared no competing interests.

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