Osteoporosis and hypertension are examples of major public health problems with significant morbidity and mortality. Coexistence of osteoporosis and hypertension, which are considered to be distinct diseases, has been observed for more than a century and suggested that they might be genetically and aetiologically related. Daily intake of calcium and sodium is known to be associated with osteoporosis and hypertension, respectively, and low calcium and high sodium dietary intake is characteristics of the Korean population. This study aims to find the role of low calcium and high sodium dietary intake in a Korean population in association with osteoporosis and hypertension. The data from Korea National Health and Nutrition Examination Survey 2008-2011 were included in this study. Osteoporosis was diagnosed by dual energy X-ray absorptiometry and hypertension was diagnosed by blood pressure data or the use of antihypertensive medication. Daily calcium and sodium intake was calculated using 24-hour dietary recall questionnaire. The odds of osteoporosis and hypertension were calculated for quartiles of daily calcium and sodium intake by logistic regression analysis. Men with hypertension had higher prevalence of osteoporosis (6.4% vs. 3.5%; p=0.002), and vice versa (22.6% vs. 13.6%; p=0.002). Women with hypertension also had high coexistence of osteoporosis (32.2% vs. 11.5%; p<0.001), and vice versa (19.6% vs. 6.2%; p<0.001). Analysis according to quartiles of calcium and sodium intake showed that only calcium was significantly associated with both diseases. We concluded that osteoporosis and hypertension are associated in Korean population, and a low dietary calcium intake could be associated with both diseases, suggesting a possible pathogenic linkage.
Disclosure: The authors declared no competing interests.