Background: Osteoporosis is one of the most common non-communicable diseases of modern society. In women, this pathology is found significantly more often than men. Diagnosis of osteopenia and osteoporosis is based on the definition of reduction of bone mineral density in patients. One of the methods allowing to determine bone loss is a dual-energy X-ray absorptiometry. During the DXA results are then compared with the reference base of the bone mineral density (BMD) that was originally put in the densitometric system equipment manufacturer. Often, however, the existing base is different from the reference population BMD patients from other regions. The objective of this study was to perform a comparative evaluation of bone mineral density of the lumbar vertebrae in women Kemerovo region with referential indices database NHANES III.
Methods: The study included 1504 women of the Kemerovo region of different age groups who underwent DXA of the first to fourth lumbar vertebrae. The results obtained BMD women Kemerovo region were compared with the database NHANES III.
Results: On the basis of the study was formed by the reference base indices of BMD of the lumbar vertebrae for the women of the Kemerovo region, taking into account the different age periods. The results showed peak values of bone mineral density of the lumbar vertebrae in women Kemerovo region correspond to the age of 20-29 years, after which, there is a ten-year period of stability indicators. After 40 years of age there is a significant decrease in bone mineral density. Comparative evaluation of the reference values in lumbar spine BMD residents of the Kemerovo region and the values of the database NHANES III revealed no differences in the age groups 16-19 years and 20-29 years. However, after the age of 30 BMD women Kemerovo region were significantly lower (p<0.05).
Conclusion: Thus, the use of a reference database developed indicators of BMD for the residents of the Kemerovo region will allow for DXA from a regional perspective that will improve the quality of diagnosis of osteoporosis.
Disclosure: The authors declared no competing interests.