ECTS Abstracts (2015) 1 P267

Muscle Strength and Physical Performance in Patients with Vitamin D Deficiency

Antimo Moretti1, Carlo Cisari2, Lorenzo Panella3, Maria Grazia Benedetti4, Piero Fiore5, Giulia Letizia Mauro6 & Giovanni Iolascon1


1Second University of Naples, Naples, Italy; 2Amedeo Avogadro University of Eastern Piedmont, Novara, Italy; 3Humanitas Clinical Institute, Rozzano, Milan, Italy; 4Rizzoli Orthopaedic Institute, Bologna, Italy; 5Università degli studi di Foggia, Foggia, Italy; 6University of Palermo, Palermo, Italy.


Background: Many observational studies and some clinical trials suggested a role of vitamin D counteracting bone and muscle loss in aging. Serum levels of 25-hydroxyvitamin D (25OHD) seem to be associated to muscle strength and physical performance. The aim of our study was to compare physical performance and muscle strength in subjects with different serum levels of vitamin D.

Methods: We compared 40 patients with vitamin D deficiency (25 OHD <30 ng/ml) to 37 subjects with normal serum levels of 25 OHD (>30 ng/ml). The muscle strength and muscle performance were, respectively, assessed with the Jamar handheld dynamometer and the Short Physical Performance Battery (SPPB).

Results: Results are shown in Table 1.

ParametersVitamin D deficiency subjects (n=40)Normal subjects (n=37)p-value
Age (years)66.9±7.2767.54±8.29NS
Body Mass Index (BMI) (kg/m2)25.37±3.5925.72±3.25NS
HGS (kg)12.81±5.1015.70±6.890.038
Gait speed<1 m/s: 25/40 (62.5%) >1m/s: 15/40 (37.5%)<1m/s: 20/37 (54.1%) >1 m/s: 17/37 (45.9%)NS
SPPB score<8: 17/40 (42.5%) >8: 23/40 (57.5%)<8: 10/37 (27%) >8: 20/37 (73%)NS

Conclusion: Subjects with hypovitaminosis resulted to have a significant reduction in muscle strength but not in physical performance.

Disclosure: The authors declared no competing interests.

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