Background: Many observational studies and some clinical trials suggested a role of vitamin D counteracting bone and muscle loss in aging. Serum levels of 25-hydroxyvitamin D (25OHD) seem to be associated to muscle strength and physical performance. The aim of our study was to compare physical performance and muscle strength in subjects with different serum levels of vitamin D.
Methods: We compared 40 patients with vitamin D deficiency (25 OHD <30 ng/ml) to 37 subjects with normal serum levels of 25 OHD (>30 ng/ml). The muscle strength and muscle performance were, respectively, assessed with the Jamar handheld dynamometer and the Short Physical Performance Battery (SPPB).
Results: Results are shown in Table 1.
|Parameters||Vitamin D deficiency subjects (n=40)||Normal subjects (n=37)||p-value|
|Body Mass Index (BMI) (kg/m2)||25.37±3.59||25.72±3.25||NS|
|Gait speed||<1 m/s: 25/40 (62.5%) >1m/s: 15/40 (37.5%)||<1m/s: 20/37 (54.1%) >1 m/s: 17/37 (45.9%)||NS|
|SPPB score||<8: 17/40 (42.5%) >8: 23/40 (57.5%)||<8: 10/37 (27%) >8: 20/37 (73%)||NS|
Conclusion: Subjects with hypovitaminosis resulted to have a significant reduction in muscle strength but not in physical performance.
Disclosure: The authors declared no competing interests.